Yazar "Wei, Wei" için listeleme
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Extracellular vesicles from hypoxia-preconditioned microglia promote angiogenesis and repress apoptosis in stroke mice via the TGF-beta/Smad2/3 pathway
Zhang, Lin; Wei, Wei; Ai, Xiaoyu; Kılıç, Ertuğrul; Hermann, Dirk M.; Venkataramani, Vivek; Baehr, Mathias; Doeppner, Thorsten R. (Springer Nature, 2021)Systemic transplantation of oxygen-glucose deprivation (OGD)-preconditioned primary microglia enhances neurological recovery in rodent stroke models, albeit the underlying mechanisms have not been sufficiently addressed. ... -
Inhibition of fatty acid synthesis aggravates brain injury, reduces blood-brain barrier integrity and impairs neurological recovery in a murine stroke model
Janssen, Lisa; Ai, Xiaoyu; Zheng, Xuan; Wei, Wei; Çağlayan, Ahmet Burak; Kılıç, Ertuğrul; Wang, Ya-chao; Hermann, Dirk M.; Venkataramani, Vivek; Baehr, Mathias; Doeppner, Thorsten R. (Frontiers Media SA, 2021)Inhibition of fatty acid synthesis (FAS) stimulates tumor cell death and reduces angiogenesis. When SH-SY5Y cells or primary neurons are exposed to hypoxia only, inhibition of FAS yields significantly enhanced cell injury. ... -
Knockdown of NEAT1 prevents post-stroke lipid droplet agglomeration in microglia by regulating autophagy
Pan, Yongli; Xin, Wenqiang; Wei, Wei; Tatenhorst, Lars; Graf, Irina; Popa-Wagner, Aurel; Gerner, Stefan T.; Huber, Sabine E.; Kılıç, Ertuğrul; Hermann, Dirk M.; Bähr, Mathias; Huttner, Hagen B.; Doeppner, Thorsten Roland (Springer Science and Business Media Deutschland GmbH, 2024)Background: Lipid droplets (LD), lipid-storing organelles containing neutral lipids like glycerolipids and cholesterol, are increasingly accepted as hallmarks of inflammation. The nuclear paraspeckle assembly transcript 1 ... -
Management of granulomatous lobular mastitis: an international multidisciplinary consensus (2021 edition)
Yuan, Qian-Qian; Xiao, Shu-Xuan; Farouk, Omar; Du, Yu-Tang; Sheybani, Fereshte; Tan, Qing Ting; Akbulut, Sami; Çetin, Kenan; Alikhassi, Afsaneh; Yaghan, Rami Jalal; Durur Subaşı, Irmak; Altıntoprak, Fatih; Eom, Tae Ik; Alper, Fatih; Hasbahçeci, Mustafa; Martinez-Ramos, David; Öztekin, Pelin Seher; Kwong, Ava; Pluguez-Turull, Cedric W.; Brownson, Kirstyn E.; Chandanwale, Shirish; Habibi, Mehran; Lan, Liu-Yi; Zhou, Rui; Zeng, Xian-Tao; Bai, Jiao; Bai, Jun-Wen; Chen, Qiong-Rong; Chen, Xing; Zha, Xiao-Ming; Dai, Wen-Jie; Dai, Zhi-Jun; Feng, Qin-Yu; Gao, Qing-Jun; Gao, Run-Fang; Han, Bao-San; Hou, Jin-Xuan; Hou, Wei; Liao, Hai-Ying; Luo, Hong; Liu, Zheng-Ren; Lu, Jing-Hua; Luo, Bin; Ma, Xiao-Peng; Qian, Jun; Qin, Jian-Yong; Wei, Wei; Wei, Gang; Xu, Li-Ying; Xue, Hui-Chao; Yang, Hua-Wei; Yang, Wei-Ge; Zhang, Chao-Jie; Zhang, Fan; Zhang, Guan-Xin; Zhang, Shao-Kun; Zhang, Shu-Qun; Zhang, Ye-Qiang; Zhang, Yue-Peng; Zhang, Sheng-Chu; Zhao, Dai-Wei; Zheng, Xiang-Min; Zheng, Le-Wei; Xu, Gao-Ran; Zhou, Wen-Bo; Wu, Gao-Song (BMC, 2022)Granulomatous lobular mastitis (GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care for patients ... -
Management of granulomatous lobular mastitis: An international multidisciplinary consensus (2021 edition) (vol 9, 20, 2022)
Yuan, Qian-Qian; Xiao, Shu-Yuan; Farouk, Omar; Du, Yu-Tang; Sheybani, Fereshte; Tan, Qing Ting; Akbulut, Sami; Çetin, Kenan; Alikhassi, Afsaneh; Yaghan, Rami Jalal; Durur Subaşı, Irmak; Altıntoprak, Fatih; Eom, Tae Ik; Alper, Fatih; Hasbahçeci, Mustafa; Martinez-Ramos, David; Öztekin, Pelin Seher; Kwong, Ava; Pluguez-Turull, Cedric W.; Brownson, Kirstyn E.; Chandanwale, Shirish; Habibi, Mehran; Lan, Liu-Yi; Zhou, Rui; Zeng, Xian-Tao; Bai, Jiao; Bai, Jun-Wen; Chen, Qiong-Rong; Chen, Xing; Zha, Xiao-Ming; Dai, Wen-Jie; Dai, Zhi-Jun; Feng, Qin-Yu; Gao, Qing-Jun; Gao, Run-Fang; Han, Bao-San; Hou, Jin-Xuan; Hou, Wei; Liao, Hai-Ying; Luo, Hong; Liu, Zheng-Ren; Lu, Jing-Hua; Luo, Bin; Ma, Xiao-Peng; Qian, Jun; Qin, Jian-Yong; Wei, Wei; Wei, Gang; Xu, Li-Ying; Xue, Hui-Chao; Yang, Hua-Wei; Yang, Wei-Ge; Zhang, Chao-Jie; Zhang, Fan; Zhang, Guan-Xin; Zhang, Shao-Kun; Zhang, Shu-Qun; Zhang, Ye-Qiang; Zhang, Yue-Peng; Zhang, Sheng-Chu; Zhao, Dai-Wei; Zheng, Xiang-Min; Zheng, Le-Wei; Xu, Gao-Ran; Zhou, Wen-Bo; Wu, Gao-Song (BMC, 2022)... -
Preconditioned extracellular vesicles from hypoxic microglia reduce poststroke AQP4 depolarization, disturbed cerebrospinal fluid flow, astrogliosis, and neuroinflammation
Xin, Wenqiang; Pan, Yongli; Wei, Wei; Tatenhorst, Lars; Graf, Irina; Popa-Wagner, Aurel; Gerner, Stefan T.; Huber, Sabine; Kılıç, Ertuğrul; Hermann, Dirk M.; Bähr, Mathias; Huttner, Hagen B.; Doeppner, Thorsten Roland (NLM (Medline), 2023)Background: Stroke stimulates reactive astrogliosis, aquaporin 4 (AQP4) depolarization and neuroinflammation. Preconditioned extracellular vesicles (EVs) from microglia exposed to hypoxia, in turn, reduce poststroke brain ... -
TGF-β1 decreases microglia-mediated neuroinflammation and lipid droplet accumulation in an in vitro stroke model
Xin, Wenqiang; Pan, Yongli; Wei, Wei; Gerner, Stefan T.; Huber, Sabine; Juenemann, Martin; Butz, Marius; Baehr, Mathias; Huttner, Hagen B.; Doeppner, Thorsten Roland (Multidisciplinary Digital Publishing Institute (MDPI), 2023)Hypoxia triggers reactive microglial inflammation and lipid droplet (LD) accumulation under stroke conditions, although the mutual interactions between these two processes are insufficiently understood. Hence, the involvement ... -
TREM2 regulates microglial lipid droplet formation and represses post-ischemic brain injury
Wei, Wei; Zhang, Lin; Xin, Wenqiang; Pan, Yongli; Tatenhorst, Lars; Hao, Zhongnan; Gerner, Stefan T.; Huber, Sabine; Juenemann, Martin; Doeppner, Thorsten Roland (Elsevier Masson s.r.l., 2024)Triggering receptor expressed on myeloid cells 2 (TREM2) is a transmembrane receptor protein predominantly expressed in microglia within the central nervous system (CNS). TREM2 regulates multiple microglial functions, ...